recoveriX Science

The clinical effectiveness was shown in a group study with 52 patients who improved in motor functions and spasticity highly significant.

- published in Frontiers in Neuroscience 2020

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The recoveriX PRO study investigated 52 patients (3.3 years after stroke) with a mean FMA-UE (Fugl-Meyer Assessment of Upper Extremities) at baseline of 17.0 points. The study showed a signifanct improvement of FMA-UE of 4.76*** points.

Severly impaired patients (FMA-UE: 0-28) improved 3.8*** points, moderatley impaired patients (FMA-UE: 29-42) improved 7.99*** points, mildly impaired patients (FMA-UE: 43-66) improved 5.29*** points. People that achieved an average classification accuracy >80 % improved by 6.5 points, people that were below 80 % had an improvement of 2.3 points.

The following tests showed additionally a significant improvement: Bartel**, Modified Ashworth Scale Wrist***, Modified Ashworth Scale Fingers***, Box and Block Test of Affected Hand**, Box and Block Test of Healthy Hand***, 9-hole PEG Test of Affected Hand*, 9-hole PEG Test of Healthy Hand***, Fahn Tremor Rating Scale of Affected Hand**, Fahn Tremor Rating Scale of Healthy Hand**, Lower Extremity Fugl Meyer Assessment*, Montreal Cognitive Assessment*, Stroop Color-Word Test**.

Other control studies go on average an improvement of 3.92 points in FMA-UE (FES, robotic movement, visual feedback). *** <0.001, ** <0.01

Stephen et al. (2012) defined the clinically important difference (CID) for moderately to minimally impaired patients in chronic stroke. This CID refers to the UE-FM improvement and is 4.25 to 7.25 points.

recoveriX achieved for moderately impaired patients 7.99 points which is higher than the CID.

For minimally impared patients, recoveriX achieved 5.29 points which is in the range of the CID.

Furthermore, the study showed that recoveriX leads to the same improvement independent of how long ago the stroke happened (Range: 6 month to 31 years).

Stephen J. et al.(2012) Clinically Important Difference for the Upper-Extremity Fugl-Meyer Sclae in People With Minimal to Moderate Impairment Due to Chronic Stroke,  Physical Therapy, Volume 92, Issue 6, 1 June 2012, Pages 791–798.

Motor Imagery

Virtual Reality

Neurorehabilitation with BCI

Functional electrical stimulation

 

Sebastián-Romagosa, M., Cho, W., Ortner, R., Murovec, N., Von Oertzen, T., Kamada, K., ... & Guger, C. (2020). Brain Computer Interface Treatment for Motor Rehabilitation of Upper Extremity of Stroke Patients—A Feasibility Study. Frontiers in Neuroscience.

Sebastián-Romagosa, M., Udina, E., Ortner, R., Dinarès-Ferran, J., Cho, W., Murovec, N., ... & Guger, C. (2020). EEG biomarkers related with the functional state of stroke patientsFrontiers in Neuroscience.

de Castro-Cros, M., Sebastian-Romagosa, M., Rodríguez-Serrano, J., Opisso, E., Ochoa, M., Ortner, R., ... & Tost, D. (2020). Effects of gamification in BCI functional rehabilitationFrontiers in Neuroscience.

Irimia, D.C., Ortner, R., Poboroniuc, M.S., Ignat, B.E. and Guger, C., (2018). High classification accuracy of a motor imagery based brain-computer interface for stroke rehabilitation training. Frontiers in Robotics and AI.

#Advisory-Board "Advisory-Board"

Advisory Board

The advisory board consists of international key experts in the fields of neuroscience, neurology and neurosurgery who are continuously contributing their experiences and clinical needs into the research, development and application of recoveriX by using the system in their clinical and research environment. These experts have a crucial interest in optimizing motor rehabilitation and maximizing the positive outcome of stroke therapy.

 

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Brendan Allison, PhD

Allison Consulting, San Diego

 

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Prof. Marian Poboroniuc, PhD

Technical University of Iasi, Romania

 

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Milena Korostenskaja, PhD

Florida Hospital for Children, US

 

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Vivek Prabhakaran, MD, PhD

University of Wisconsin, US

 

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Tetsuo Ota, MD, PhD

Asahikawa Medical University, Japan

 

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Rossella Spataro, MD, PhD

University of Palermo, Italy

 

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Kyosuke Kamada, MD, PhD

Mengumino Hospital, Sapporo, Japan

 

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Adam Hebb, MD, PhD

St. Joseph's Hospital, Denver, US

 

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Jing Jin, PhD

East China University of Science and Technology, China